The Inflammatory Root of Acne: A Closer Look at Skin's Silent Aggressor
If you’re grappling with acne, this paper is essential reading. Explore the work of esteemed scholars Prof. Dr. med. Harald Gollnick and Dr. James J. Leyden, representing the Global Alliance to Improve Outcomes in Acne, to grasp the underlying causes of acne. The article titled “Understanding Innate Immunity and Inflammation in Acne: Implications for Management” was initially published in the Journal of the European Academy of Dermatology and Venereology, Volume 29, Issue S4.
Background of the Scholars and Organization
Prof. Dr. med. Harald Gollnick , Director of the University Clinic for Dermatology and Venereology at the Otto von Guericke University Magdeburg, was appointed in his role as President of the European Board of Dermatology and Venereology, section of the UEMS (Association of European Specialist Groups). (link)
Dr. James J. Leyden served as Director of the American Academy of Dermatology and Chairman of the Board of the Dermatology Foundation. He is the recipient of numerous awards, including five from the American Academy of Dermatology and the Dermatology Foundation’s Distinguished Service Medallion. He has also been incredibly generous to the field of Dermatology, especially through the Dermatology Foundation. (link)
The Global Alliance to Improve Outcomes in Acne is an international group of dermatologists with an interest in acne research and education that has been meeting regularly since 2001. The Global Alliance to Improve Outcomes in Acne is esteemed for its comprehensive approach to acne research, education, and management on an international scale, significantly contributing to improvements in patient care and outcomes.
Key Information of the Article
The article discusses the role of inflammation in acne, focusing on the activation of innate immunity within the follicular environment. Key points include:
- Acne’s pathogenesis involves sebum production, keratinization, and immune response to Propionibacterium acnes.
- Inflammation is present at all acne stages, emphasizing its central role in the condition.
- The study examines how different factors, like immune cells and cytokines, contribute to acne’s inflammatory process.
- It also explores the impact of treatment strategies on inflammation and the innate immune system in acne management.
Cite from:
Dreno, B., Gollnick, H. P., Kang, S., Thiboutot, D., Bettoli, V., Torres, V., Leyden, J., & Global Alliance to Improve Outcomes in Acne (2015). Understanding innate immunity and inflammation in acne: implications for management. Journal of the European Academy of Dermatology and Venereology : JEADV, 29 Suppl 4, 3–11. https://doi.org/10.1111/jdv.13190
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